CBD Research For The Treatment Of Cancer

In the United States, cannabinoids have been allowed for use in palliative medicine due to their effectiveness for pain-relief and effectiveness against vomiting and nausea, but increasing number of research studies have investigated and indicated their anticancer properties.

Research from the NCBI

The National Center for Biotechnology Information (NCBI) advances science and health by providing access to biomedical and genomic information. PubMed, one of many resources on NCBI’s website comprises more than 28 mission citations or biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher websites.

The following is a partial list of cancer research studies which have been published on the NCBI’s website.

General Cancer Research

Cannabidiol as potential anticancer drug

Cannabidiol inhibits angiogenesis by multiple mechanisms

The inhibitory effects of cannabidiol on systemic malignant tumors

Cannabidiol inhibits cancer cell invasion via up regulation of tissue inhibitor of matrix metalloproteinases-1

Lung Cancer Research

Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1C

COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells

Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells

Prostate / Colon Cancer Research

Towards the use of non-psychoactive cannabinoids for prostate cancer

Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent

Chemo preventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

Breast Cancer Research

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross talk between apoptosis and autophagy

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis

Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration

Glioblastoma / Brain Cancer Research

Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines(PubMed)

Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas

Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism

Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target

Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents

Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect

Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme

Leukemia Cancer Research

Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression

Cannabidiol-Induced Apoptosis in Human Leukemia Cells

Skin Cancer Research

Anticancer activity of anandamide in human cutaneous melanoma cells

Kaposi Sarcoma Cancer Research

Cannabidiol inhibits growth and induces programmed cell death in Kaposi Sarcoma-associated herpes virus-infected endothelium (PubMed)

Endocrine Cancer Research

Endocannabinoids in endocrine and related tumors

A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells

Bladder Cancer Research

TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: a potential therapeutic target for bladder cancer

Pain in Cancer Patients Research

Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain

Nabiximols for opioid-treated cancer patients with poorly controlled chronic pain: a randomized, placebo-controlled, graded-dose trial

About Diverse Biotech, Inc.

Diverse Biotech Inc. is an innovative, clinical-stage biopharmaceutical research company, committed to discovering and developing novel therapeutics from its proprietary cannabinoid product platform.

For more information on Diverse Biotech or its Cannabinoid (CBD) clinical trials, use in the treatment of specific types of malignancies related to glioblastoma, myeloma, gastrointestinal, and breast cancer, when administered in conjunction with Standard of Care, please contact Diverse Biotech by phone at 407-776-9217 or visit the company’s headquarters at 805 S. Kirkman Rd, Suite 202, Orlando, Florida 32811.